Also Known As
Thyroid Function Panel, Thyroid Profile with TSH, Thyroid Blood Test
What Is a Thyroid Panel with TSH?
A thyroid panel with TSH is a comprehensive blood test that evaluates how well your thyroid gland is functioning. It measures three key markers — TSH (thyroid-stimulating hormone), Total T4 (thyroxine), and T3 Uptake — to screen for thyroid disorders including hypothyroidism, hyperthyroidism, Hashimoto’s disease, and Graves’ disease.
According to the American Thyroid Association, thyroid disorders affect an estimated 20 million Americans. The thyroid is a small butterfly-shaped gland in your neck that regulates metabolism, energy, body temperature, heart rate, and mood. Even minor imbalances in thyroid hormone levels can cause wide-ranging symptoms that affect your quality of life. This panel gives you and your healthcare provider a clear picture of your thyroid status without a doctor’s visit or insurance.
What Does the Thyroid Panel Measure?
| Marker | What It Measures |
|---|---|
| TSH | Pituitary signal telling the thyroid to produce hormones; the primary screening marker |
| Total T4 (Thyroxine) | Main hormone produced by the thyroid gland |
| T3 Uptake | Reflects how much T3 is available and bound to carrier proteins |
Together these markers help identify whether your thyroid is underactive (hypothyroidism), overactive (hyperthyroidism), or functioning normally.
Who Should Get a Thyroid Panel with TSH?
Consider this test if you experience any of the following:
Symptoms of hypothyroidism (underactive thyroid):
- Persistent fatigue or low energy
- Unexplained weight gain
- Cold intolerance
- Depression or brain fog
- Dry skin, brittle nails, or hair loss
- Constipation
- Slow heart rate
Symptoms of hyperthyroidism (overactive thyroid):
- Unexplained weight loss
- Rapid or irregular heartbeat
- Anxiety or nervousness
- Heat intolerance and excessive sweating
- Frequent bowel movements
- Tremors or muscle weakness
Also recommended for:
- Anyone with a family history of thyroid disease
- Women over 35 (thyroid disorders are significantly more common in women)
- People with autoimmune conditions
- Patients currently being treated for thyroid disorders who need monitoring
- Anyone experiencing unexplained fatigue, weight changes, or mood shifts
Thyroid Panel Reference Ranges
| Marker | Normal Range |
|---|---|
| TSH | 0.4 – 4.0 mIU/L |
| Total T4 | 4.5 – 12.5 mcg/dL |
| T3 Uptake | 24 – 39% |
High TSH + Low T4 = hypothyroidism (underactive thyroid) Low TSH + High T4 = hyperthyroidism (overactive thyroid)
Reference ranges may vary by laboratory. Always review results with a qualified healthcare provider. For a more detailed picture, consider our Optimal Thyroid Panel.
Test Preparation
No fasting is required. If you are currently taking thyroid medication (such as levothyroxine), have your blood drawn before your morning dose for the most accurate TSH reading. Otherwise, no special preparation is needed.
How Much Does a Thyroid Panel with TSH Cost?
| Where You Get Tested | Typical Cost |
|---|---|
| Personalabs | [current price] — physician order included |
| Doctor’s office + lab | $200–$400+ |
| Hospital outpatient lab | $250–$500+ |
HSA and FSA eligible.
Frequently Asked Questions
What is the difference between TSH alone and a full thyroid panel? A TSH-only test is the standard first-line screening. Adding T4 and T3 Uptake gives a more complete picture — particularly useful if your TSH is borderline or if you have symptoms despite a normal TSH.
Can I have thyroid problems with a normal TSH? Yes. Some people experience symptoms even with TSH in the normal range, particularly if Free T3 conversion is impaired. If symptoms persist, consider upgrading to the Basic Thyroid Health Profile which includes Free T3 and Free T4.
How long does it take to get results? Results are typically available in your Personalabs account within 24–48 hours of your blood draw.
Can I order a thyroid panel without a doctor? Yes — in most states. Personalabs includes a physician-approved lab order with every purchase. No referral or insurance needed. Our network physician approves your order within 2–4 hours.
Is this test HSA/FSA eligible? Yes. Thyroid testing qualifies as a reimbursable medical expense under HSA and FSA plans.
What thyroid conditions can this panel detect? This panel can help identify hypothyroidism, hyperthyroidism, Hashimoto’s thyroiditis, Graves’ disease, thyroiditis, goiter, and abnormal thyroid hormone binding.
Where Can I Get a Thyroid Panel Near Me?
Personalabs partners with Labcorp and Quest Diagnostics, giving you access to more than 4,000 lab locations nationwide. Use our lab locator to find a collection site near you. Results are delivered securely to your Personalabs account within 24–48 hours.

